Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17061425 | 0.91 | THRB (0.47) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL10661691 | 0.91 | THRB (0.47) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL17061427 | 0.91 | THRB (0.47) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL10622893 | 0.88 | THRB (0.45) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL9763982 | 0.88 | THRB (0.45) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL10657434 | 0.86 | THRB (0.43) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL9764056 | 0.85 | HCAR2 (0.38) | ALDH1A1TDP1MAPTAKR1B10AKR1B1 | |
| SCHEMBL16788735 | 0.85 | THRB (0.42) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL4661264 | 0.85 | THRB (0.51) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL25755694 | 0.84 | THRB (0.41) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |