Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622762 | 0.86 | THRB (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL10644010 | 0.85 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL17373011 | 0.85 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL10625213 | 0.85 | THRB (0.54) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL15361866 | 0.85 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL9763728 | 0.85 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL13863126 | 0.85 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL13863119 | 0.85 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL4623580 | 0.84 | HCAR2 (0.40) | ALDH1A1TDP1MAPTHCAR2AKR1B10 | |
| SCHEMBL17061425 | 0.83 | THRB (0.47) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947393-B2 | Coating agent | NIPPON SODA CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| US-10947393-B2 | Coating agent | NIPPON SODA CO., LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-2949716-B1 | COATING AGENT | NIPPON SODA CO (JP) | 2020-04-29 | — | — | EP | disclosed |
| US-20150353738-A1 | COATING AGENT | NIPPON SODA CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353738-A1 | COATING AGENT | NIPPON SODA CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353738-A1 | COATING AGENT | NIPPON SODA CO., LTD. (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2949716-A1 | COATING AGENT | Nippon Soda Co., Ltd. (JP) | 2015-12-02 | — | — | EP | disclosed |
| EP-1444239-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB (US) | 2008-12-24 | — | — | EP | disclosed |
| US-7132494-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-6881809-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| US-6846897-B2 | High refractive index aromatic-based silyl monomers | BAUSCH AND LOMB, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040230023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040215156-A1 | High refractive index aromatic-based silyl monomers | SOLTA MEDICAL, INC. | 2004-10-28 | — | — | US | disclosed |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C | 2004-10-28 | — | — | US | disclosed |
| US-20040210023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-10-21 | — | — | US | disclosed |
| EP-1444239-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6762271-B2 | INTRAOCULAR LENSES, CONTACT LENSES AND CORNEAL INLAYS | BAUSCH & LOMB INCORPORATED | 2004-07-13 | — | — | US | disclosed |
| US-20030105255-A1 | High refractive index aromatic-based silyl monomers | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2003-06-05 | — | — | US | disclosed |
| WO-2003040152-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353738-A1 | COATING AGENT | ITGA1, ITGA2, L1CAM | THRB 3589/4885TSHR 3363/4885HPGD 3568/4885 |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SMAD2, SMAD3, FHIT | THRB 4416/4885TSHR 4336/4885HPGD 3207/4885 |
| US-10947393-B2 | Coating agent | ITGA1, ITGA2, L1CAM | THRB 3589/4885TSHR 3363/4885HPGD 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.