Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764056 | 0.89 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL1398281 | 0.88 | HCAR2 (0.37) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL9763982 | 0.86 | THRB (0.45) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL16205020 | 0.84 | HCAR2 (0.38) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL17061425 | 0.84 | THRB (0.47) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL10629493 | 0.83 | HCAR2 (0.41) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL22092326 | 0.82 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL4623580 | 0.82 | HCAR2 (0.40) | HCAR2AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL8640131 | 0.81 | ATM (0.44) | HCAR2ALDH1A1MAPTATM | |
| SCHEMBL1632990 | 0.81 | ATM (0.44) | HCAR2ALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |