Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14070022 | 0.88 | LMNA (0.64) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL27869197 | 0.78 | LMNA (0.55) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL11618977 | 0.78 | ALDH1A1 (0.44) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL268773 | 0.77 | TDP1 (0.44) | LMNAALDH1A1TDP1KMT2AERN1 | |
| SCHEMBL2558670 | 0.77 | CA2 (0.49) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL30250019 | 0.77 | CYP3A4 (0.57) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL10635467 | 0.77 | CYP3A4 (0.57) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL4033357 | 0.75 | ALDH1A1 (0.69) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL13850503 | 0.75 | LMNA (0.51) | LMNAHPGDALDH1A1TDP1HSD17B10 | |
| SCHEMBL2890802 | 0.74 | HPGD (0.59) | LMNAHPGDALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237434-B1 | SUBSTITUTED 2,3-NAPHTHALENEDICARBOXALDEHYDES | OREAD LABORATORIES, INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4723022-A | Substituted 2,3-naphthalenedicarboxaldehydes | OREAD LABORATORIES, INC. (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0237434-A2 | Substituted 2,3-naphthalenedicarboxaldehydes | OREAD LABORATORIES, INC. (US) | 1987-09-16 | — | — | EP | disclosed |