SCHEMBL9763904

SCHEMBL9763904

CCc1cnc(-c2cc(F)c(F)c(F)c2)nc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.37
GRIN2B Q13224 14/20 0.34
GRIN1 Q05586 10/20 0.33
RXRA P19793 7/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
HSD17B10 Q99714 1/20 0.33
OPRL1 P41146 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763981 0.90 RXRA (0.37) ACACBGRIN2BGRIN1RXRANPC1
SCHEMBL9764309 0.85 RAB9A (0.43) GRIN2BNPC1RAB9ASMN1; SMN2TP53
SCHEMBL9763609 0.82 RARB (0.46) NPC1RAB9ASMN1; SMN2TP53PKM
SCHEMBL10719819 0.81 GRIN2B (0.43) ACACBGRIN2BGRIN1RXRANPC1
SCHEMBL9507105 0.81 RARB (0.51) NPC1RAB9ASMN1; SMN2TP53PKM
SCHEMBL9511660 0.81 TRPV4 (0.39) ACACBSMN1; SMN2
SCHEMBL9763848 0.80 RARB (0.54) NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL9763897 0.80 RARB (0.54) NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL9763490 0.80 RARB (0.54) NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL15829128 0.80 ACACB (0.34) ACACBGRIN2BGRIN1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed