Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 9/20 | 0.53 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763826 | 0.81 | AHCY (0.52) | AHCYTK1HDAC6KDM4EALDH1A1 | |
| SCHEMBL9763828 | 0.81 | AHCY (0.52) | AHCYTK1HDAC6KDM4EALDH1A1 | |
| SCHEMBL9763834 | 0.81 | AHCY (0.52) | AHCYTK1HDAC6KDM4EALDH1A1 | |
| SCHEMBL469371 | 0.79 | HDAC6 (0.49) | AHCYTK1HDAC6KDM4EALDH1A1 | |
| SCHEMBL4551666 | 0.79 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL3151968 | 0.77 | KDM4E (0.55) | TK1HDAC6KDM4EALDH1A1HPGD | |
| SCHEMBL9116846 | 0.74 | KDM4E (0.53) | TK1HDAC6KDM4EALDH1A1HPGD | |
| Detiviciclovir SCHEMBL7744996 | 0.74 | KDM4E (0.52) | AHCYHDAC6KDM4EALDH1A1HPGD | |
| SCHEMBL14642669 | 0.73 | CDK1 (0.56) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL9776612 | 0.72 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036071-A | Herper virus | MEDIVIR AB (SE) | 1991-07-30 | — | — | US | claimed |
| EP-0186640-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1990-02-07 | — | — | EP | claimed |
| EP-0186640-A1 | Derivatives of purine, process for their preparation and a pharmaceutical preparation | Medivir Aktiebolag (SE) | 1986-07-02 | — | — | EP | claimed |
| US-5036071-A | Herper virus | MEDIVIR AB (SE) | 1991-07-30 | — | — | US | disclosed |
| EP-0186640-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0186640-A1 | Derivatives of purine, process for their preparation and a pharmaceutical preparation | Medivir Aktiebolag (SE) | 1986-07-02 | — | — | EP | disclosed |