Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 9/20 | 0.33 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764243 | 0.78 | DUT (0.40) | MEN1KMT2ANPC1DUTGAA | |
| SCHEMBL8865301 | 0.74 | DUT (0.44) | NPC1DUTGAA | |
| SCHEMBL10415297 | 0.72 | LMNA (0.35) | DUT | |
| SCHEMBL10416085 | 0.72 | LMNA (0.35) | DUT | |
| SCHEMBL4711900 | 0.71 | KMT2A (0.48) | KMT2ANPC1DUT | |
| SCHEMBL21389245 | 0.70 | KMT2A (0.42) | MEN1KMT2ANPC1PIK3CDDUT | |
| SCHEMBL10724599 | 0.69 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL23042973 | 0.69 | — | — | |
| SCHEMBL14119498 | 0.69 | — | — | |
| SCHEMBL16709051 | 0.69 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223588-B1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-12 | — | — | EP | disclosed |