Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2457805 | 0.75 | KDM4E (0.47) | SMN1; SMN2GAAMAP4K4PRKACACDK8 | |
| SCHEMBL2457803 | 0.75 | KDM4E (0.47) | SMN1; SMN2GAAMAP4K4PRKACACDK8 | |
| Hydrochloric Acid SCHEMBL29051256 | 0.73 | LMNA (0.43) | SMN1; SMN2GAALMNATDP1MAPK1 | |
| Bromide SCHEMBL28350490 | 0.71 | LMNA (0.48) | SMN1; SMN2GAALMNATDP1MAPK1 | |
| SCHEMBL6209010 | 0.71 | KDM4E (0.48) | SMN1; SMN2GAAMAP4K4PRKACACDK8 | |
| SCHEMBL6209007 | 0.71 | KDM4E (0.48) | SMN1; SMN2GAAMAP4K4PRKACACDK8 | |
| SCHEMBL28879040 | 0.70 | GRM4 (0.41) | SMN1; SMN2MAP4K4PRKACACDK8MAPK14 | |
| SCHEMBL2866599 | 0.69 | GAA (0.51) | SMN1; SMN2GAAMAP4K4PRKACACDK8 | |
| SCHEMBL28314253 | 0.69 | MAOB (0.38) | CYP11B1CYP11B2MAOBALDH1A1KMT2A | |
| SCHEMBL19596477 | 0.66 | LMNA (0.43) | SMN1; SMN2GAALMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906330-A1 | COATED ION EXCHANGE MEMBRANES | Evoqua Water Technologies LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-2903737-A1 | HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME | Evoqua Water Technologies LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014055123-A1 | HIGH-PERFORMANCE ANION EXCHANGE MEMBRANES AND METHODS OF MAKING SAME | EVOQUA WATER TECHNOLOGIES LLC (US) | 2014-04-10 | — | — | WO | disclosed |
| US-5018380-A | Organometallic gas carrier in interpenetrating polymer network | ALLIED-SIGNAL INC. (US) | 1991-05-28 | — | — | US | disclosed |
| US-4627859-A | ORGANOMETALLIC GAS CARRIER INTERDISPERSED IN INTERPENE TRATING POLYMER NETWORK MATRIX | ALLIED CORPORATION (US) | 1986-12-09 | — | — | US | disclosed |