Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169090 | 0.91 | SIRT2 (0.42) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL21139494 | 0.91 | HTR2C (0.40) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL4334443 | 0.83 | ALDH1A1 (0.55) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL10788404 | 0.78 | KDM4E (0.44) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL1639715 | 0.77 | GAA (0.59) | GAAALDH1A1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL5080663 | 0.75 | ALOX15 (0.56) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL8047112 | 0.75 | KDM4E (0.61) | HTR2CTLR8ALDH1A1KMT2AKDM4E | |
| SCHEMBL1446334 | 0.75 | LMNA (0.61) | HTR2CGAAALDH1A1KMT2AKDM4E | |
| SCHEMBL9193305 | 0.75 | HTR2C (0.45) | HTR2CTLR8GAAALDH1A1KMT2A | |
| SCHEMBL13676821 | 0.74 | KDM4E (0.48) | GAAALDH1A1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987258-A | Intermediates for disazo dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0196574-B1 | 4,4'-DIAMINODIPHENYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0196574-A2 | 4,4'-Diaminodiphenyl compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-08 | — | — | EP | disclosed |