Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE1A | P54750 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764402 | 1.00 | NPC1 (0.40) | NPC1RAB9APDE7APDE4DPDE1A | |
| SCHEMBL9764378 | 0.81 | NPC1 (0.40) | NPC1RAB9APDE7APDE4DPDE1A | |
| SCHEMBL11126928 | 0.65 | MAPT (0.37) | NPC1RAB9APDE7APDE4DPDE1A | |
| SCHEMBL9764683 | 0.63 | SMN1; SMN2 (0.34) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL9764336 | 0.63 | SMN1; SMN2 (0.34) | KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11358963 | 0.60 | SMN1; SMN2 (0.41) | GAAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11140863 | 0.60 | GAA (0.35) | PDE7APDE4DPDE1APDE1BPDE1C | |
| SCHEMBL11372122 | 0.59 | ALDH1A1 (0.41) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL11374537 | 0.59 | ALDH1A1 (0.41) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL11376371 | 0.57 | ALDH1A1 (0.41) | GAAKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33745-E | Thiadiazabicyclononane derivatives, processes for their production and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0238711-B1 | THIADIAZABICYCLONONANE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND HERBIZIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |
| US-4816063-A | PLANT GROWTH REGULATORS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0238711-A1 | Thiadiazabicyclononane derivatives, processes for their production and herbizidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |