Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762676 | 0.84 | SIGMAR1 (0.52) | SIGMAR1BCHES1PR1S1PR3S1PR2 | |
| Oxalic Acid SCHEMBL31621151 | 0.84 | SIGMAR1 (0.69) | SIGMAR1BCHES1PR1MAOAKDM4E | |
| SCHEMBL456614 | 0.83 | SIGMAR1 (0.80) | SIGMAR1BCHECNR1CNR2MAOA | |
| Hydrochloric Acid SCHEMBL9257562 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHECNR1CNR2MAOA | |
| Hydrochloric Acid SCHEMBL9254084 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHECNR1CNR2MAOA | |
| Bromide SCHEMBL7121198 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHECNR1CNR2MAOA | |
| Hydrochloric Acid SCHEMBL454214 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHECNR1CNR2MAOA | |
| SCHEMBL27496896 | 0.81 | SIGMAR1 (0.77) | SIGMAR1BCHECNR1CNR2MAOA | |
| SCHEMBL10465008 | 0.81 | SIGMAR1 (0.53) | SIGMAR1BCHES1PR1S1PR3S1PR2 | |
| SCHEMBL27851927 | 0.80 | SIGMAR1 (0.67) | SIGMAR1BCHECNR1CNR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |