Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764540 | 0.84 | SIGMAR1 (0.55) | SIGMAR1BCHEKMT2AS1PR1S1PR3 | |
| SCHEMBL9764536 | 0.83 | SCN8A (0.57) | SIGMAR1BCHEACHEKMT2A | |
| SCHEMBL9763358 | 0.83 | SIGMAR1 (0.51) | SIGMAR1BCHEACHEKMT2A | |
| Oxalic Acid SCHEMBL31621151 | 0.82 | SIGMAR1 (0.69) | SIGMAR1BCHEACHEKMT2AS1PR1 | |
| SCHEMBL9762664 | 0.81 | SIGMAR1 (0.49) | SIGMAR1BCHEACHESPHK1 | |
| SCHEMBL456614 | 0.81 | SIGMAR1 (0.80) | SIGMAR1BCHECNR1CNR2 | |
| SCHEMBL9763305 | 0.80 | BCHE (0.46) | SIGMAR1BCHEACHEKMT2ASLC2A1 | |
| SCHEMBL9762627 | 0.80 | SIGMAR1 (0.52) | SIGMAR1BCHES1PR1S1PR3CNR1 | |
| SCHEMBL11346386 | 0.80 | PTGES (0.58) | KMT2AS1PR1S1PR3LTA4HS1PR5 | |
| SCHEMBL9762667 | 0.80 | SLC2A1 (0.50) | SIGMAR1BCHEACHEKMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |