Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343289 | 0.84 | KMT2A (0.40) | KDM4ELMNAHTTNPC1RAB9A | |
| SCHEMBL8830149 | 0.83 | LTA4H (0.42) | LMNAHTTRAB9ASLC6A2SLC6A4 | |
| SCHEMBL9342673 | 0.82 | KMT2A (0.47) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL9340514 | 0.82 | RAB9A (0.45) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9764726 | 0.79 | PTGS1 (0.46) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL12212314 | 0.75 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL570633 | 0.75 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL9338875 | 0.75 | HTR2A (0.46) | KDM4ELMNASLC6A4KMT2ACYP2C19 | |
| SCHEMBL3839100 | 0.74 | ALDH1A1 (0.58) | LMNAHTTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10990594 | 0.73 | SLC6A4 (0.50) | LMNAHTTSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |