Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.47 |
| ▸ | MAOA | P21397 | 10/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534470 | 0.81 | KDM1A (0.44) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL9754878 | 0.77 | KDM1A (0.46) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL10507213 | 0.76 | MAPT (0.50) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL5078776 | 0.73 | KDM1A (0.43) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL10747925 | 0.72 | KDM1A (0.50) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL4331068 | 0.72 | KDM1A (0.67) | KDM1AMAOAMAOB | |
| SCHEMBL3198171 | 0.72 | CYP2C19 (0.44) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL8676674 | 0.72 | KDM1A (0.42) | KDM1AMAOAMAOBGAAMAPT | |
| SCHEMBL3536966 | 0.72 | KDM1A (0.42) | KDM1AMAOAMAOBNFKB1NFKB2 | |
| SCHEMBL8677375 | 0.70 | MAPT (0.53) | KDM1AMAOAMAOBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240188565-A1 | GLOBODERA PALLIDA CONTROL AGENT | NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (JP) | 2024-06-13 | — | — | US | disclosed |
| EP-4298907-A1 | GLOBODERA PALLIDA CONTROL AGENT | NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (JP) | 2024-01-03 | — | — | EP | disclosed |
| WO-2022181170-A1 | GLOBODERA PALLIDA CONTROL AGENT | 国立研究開発法人農業・食品産業技術総合研究機構 | 2022-09-01 | — | — | WO | disclosed |
| EP-0403487-A4 | NOVEL HMG-COA REDUCTASE INHIBITORS | — | 1991-06-05 | — | — | EP | disclosed |
| EP-0403487-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4863957-A | ANTICHOLESTEROL AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| WO-1989005639-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240188565-A1 | GLOBODERA PALLIDA CONTROL AGENT | GHRHR, BRIX1, RBX1 | KDM1A 439/4885MAOA 1974/4885MAOB 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.