Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347596 | 0.92 | ADRB2 (0.40) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9800394 | 0.88 | ADRB2 (0.41) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL5918471 | 0.88 | ADRB2 (0.56) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7558473 | 0.87 | ADRB2 (0.54) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL5918480 | 0.87 | ADRB2 (0.42) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL10494711 | 0.86 | ADRB2 (0.47) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9262753 | 0.85 | ADRB2 (0.40) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL917269 | 0.85 | HTR6 (0.56) | ADRB2HTR1DHTR2AHTR6LMNA | |
| SCHEMBL9597232 | 0.85 | NQO2 (0.43) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL10494710 | 0.84 | ADRB2 (0.40) | ADRB2HTR1DNQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |