Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800340 | 0.88 | HTR1D (0.54) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9765108 | 0.88 | ADRB2 (0.42) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9800377 | 0.86 | ADRB2 (0.46) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9800355 | 0.85 | HTR6 (0.55) | ADRB2HTR1DHTR2AHTR6 | |
| SCHEMBL9800333 | 0.85 | NQO2 (0.42) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9800379 | 0.84 | HTR6 (0.54) | ADRB2HTR1DHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL27673725 | 0.84 | ADRB2 (0.39) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| SCHEMBL9800350 | 0.83 | ADRB2 (0.43) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9800409 | 0.83 | NQO2 (0.41) | ADRB2HTR1DNQO2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9800411 | 0.83 | HTR6 (0.53) | ADRB2HTR1DHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |
| CN-85104233-A | Chemical compound | — | 1987-01-07 | — | — | CN | disclosed |