Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 9/20 | 0.65 |
| ▸ | HTR1B | P28222 | 9/20 | 0.65 |
| ▸ | HTR1A | P08908 | 7/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.65 |
| ▸ | HTR5A | P47898 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR1E | P28566 | 1/20 | 0.65 |
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800423 | 0.88 | HTR1B (0.54) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL10465856 | 0.85 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Dimethylamine SCHEMBL8927414 | 0.84 | HTR1D (0.71) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL10494772 | 0.83 | CSNK2A1 (0.56) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL10465307 | 0.82 | CSNK2A1 (0.47) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL10465878 | 0.82 | HTR2A (0.50) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL13926193 | 0.82 | HTR1D (0.76) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL5918470 | 0.81 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL2739183 | 0.81 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL9456487 | 0.81 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736878-B2 | Treatment of organophosphate exposure with triptans | PFADENHAUER TINA (US) | 2020-08-11 | — | — | US | disclosed |
| US-20140024641-A1 | TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH TRIPTANS | HELTON DAVID REED (US) | 2014-01-23 | — | — | US | disclosed |
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |
| US-4816470-A | Heterocyclic compounds | GLAXO GROUP LIMITED | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024641-A1 | TREATMENT OF ORGANOPHOSPHATE EXPOSURE WITH TRIPTANS | DDT, THOP1, TPP1 | HTR1D 945/4885HTR1B 1868/4885HTR1A 957/4885 |
| US-10736878-B2 | Treatment of organophosphate exposure with triptans | DDT, THOP1, TPP1 | HTR1D 945/4885HTR1B 1868/4885HTR1A 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.