Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 11/20 | 0.54 |
| ▸ | HTR1D | P28221 | 10/20 | 0.54 |
| ▸ | HTR1A | P08908 | 10/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR5A | P47898 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR1F | P30939 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765114 | 0.88 | HTR1D (0.65) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800403 | 0.84 | CSNK2A1 (0.53) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800390 | 0.83 | CSNK2A1 (0.50) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800399 | 0.83 | HTR1A (0.57) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800384 | 0.83 | HTR1D (0.59) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800332 | 0.83 | HTR1A (0.59) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800335 | 0.83 | HTR1A (0.61) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800422 | 0.81 | HTR1A (0.77) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL9800405 | 0.81 | HTR1A (0.77) | HTR1BHTR1DHTR1AHTR2AHTR7 | |
| SCHEMBL9800369 | 0.81 | HTR1A (0.57) | HTR1BHTR1DHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |