Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707019 | 0.85 | ALDH1A1 (0.49) | TDP1KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL30079307 | 0.82 | TSHR (0.63) | TSHRTDP1KDM4ERECQLKMT2A | |
| SCHEMBL9765252 | 0.80 | TBXA2R (0.48) | TSHRTDP1KDM4EALDH1A1GAA | |
| SCHEMBL3936350 | 0.79 | ALDH1A1 (0.44) | TSHRTDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL3936345 | 0.79 | ALDH1A1 (0.44) | TSHRTDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL9765317 | 0.79 | PTGS2 (0.52) | TSHRTDP1KDM4EALDH1A1EGFR | |
| SCHEMBL6271065 | 0.74 | ALDH1A1 (0.66) | KDM4EKMT2AALDH1A1CA1CA2 | |
| SCHEMBL12279884 | 0.72 | ALDH1A1 (0.48) | KDM4EKMT2AALDH1A1GAAHTT | |
| SCHEMBL12279267 | 0.72 | EGFR (0.55) | TDP1KDM4ERECQLKMT2AALDH1A1 | |
| SCHEMBL4781214 | 0.72 | CA1 (0.61) | TSHRTDP1KDM4ERECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |