Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765309 | 0.87 | ALDH1A1 (0.50) | HTTTHRBALDH1A1MAPTHSD17B10 | |
| SCHEMBL9765315 | 0.83 | HTT (0.49) | HTTTHRBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL16929960 | 0.80 | KMT2A (0.57) | ADRA1DADRA1AADRA1BHTTBCHE | |
| SCHEMBL9765299 | 0.80 | SMN1; SMN2 (0.51) | HTTALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL5018761 | 0.79 | MEN1 (0.58) | BCHEALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL20058881 | 0.78 | TRPM8 (0.55) | ADRA1DADRA1AADRA1BHTTBCHE | |
| SCHEMBL27284050 | 0.77 | ALDH1A1 (0.71) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6795931 | 0.76 | MEN1 (0.55) | BCHECYP1A2CYP2C9NPC1RAB9A | |
| SCHEMBL27598330 | 0.76 | BCHE (0.58) | BCHEALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL9765301 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |