Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765324 | 0.83 | ALDH1A1 (0.48) | SMN1; SMN2HPGDHTTPOLBKMT2A | |
| SCHEMBL28344001 | 0.80 | NPC1 (0.56) | SMN1; SMN2HPGDNPC1RAB9ACA1 | |
| SCHEMBL28344002 | 0.80 | NPC1 (0.56) | SMN1; SMN2HPGDNPC1RAB9ACA1 | |
| SCHEMBL9765288 | 0.80 | ADRA1D (0.56) | HPGDNPC1RAB9AHTTPOLB | |
| SCHEMBL9765264 | 0.76 | KCNA5 (0.55) | SMN1; SMN2NPC1RAB9AHTTPOLB | |
| SCHEMBL9765306 | 0.76 | KCNA5 (0.55) | SMN1; SMN2NPC1RAB9AHTTPOLB | |
| SCHEMBL7860111 | 0.76 | F7 (0.58) | CA1CA2ACHEF2F10 | |
| SCHEMBL12738664 | 0.75 | NPC1 (0.55) | SMN1; SMN2HPGDNPC1RAB9AF2 | |
| SCHEMBL16973419 | 0.74 | HPGD (0.50) | SMN1; SMN2HPGDNPC1RAB9ACA1 | |
| SCHEMBL19734616 | 0.73 | NPC1 (0.57) | SMN1; SMN2HPGDNPC1RAB9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |