Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765318 | 0.86 | ALDH1A1 (0.46) | ALDH1A1ATML3MBTL1MMP9KCNA5 | |
| SCHEMBL9765264 | 0.82 | KCNA5 (0.55) | ALDH1A1ATML3MBTL1HTTMMP9 | |
| SCHEMBL9765306 | 0.82 | KCNA5 (0.55) | ALDH1A1ATML3MBTL1HTTMMP9 | |
| SCHEMBL9765258 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ATML3MBTL1MAPTHTT | |
| SCHEMBL11103819 | 0.79 | L3MBTL1 (0.53) | ALDH1A1ATML3MBTL1KCNA5SMN1; SMN2 | |
| SCHEMBL9765262 | 0.79 | ALDH1A1 (0.53) | CYP1A2CYP2C9CYP2C19ALDH1A1ATM | |
| SCHEMBL11108374 | 0.77 | ALDH1A1 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1ATM | |
| SCHEMBL15388015 | 0.76 | MAPT (0.58) | GAAALDH1A1ATML3MBTL1LMNA | |
| SCHEMBL1287475 | 0.76 | MAPT (0.58) | GAAALDH1A1ATML3MBTL1LMNA | |
| SCHEMBL15388142 | 0.73 | ALDH1A1 (0.60) | CYP1A2GAACYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |