Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765306 | 1.00 | KCNA5 (0.55) | KCNA5ALDH1A1POLBCNR1EGFR | |
| SCHEMBL9765258 | 0.83 | ALDH1A1 (0.57) | ALDH1A1POLBATML3MBTL1HTT | |
| SCHEMBL9765318 | 0.82 | ALDH1A1 (0.46) | KCNA5ALDH1A1CNR1EGFRERBB2 | |
| SCHEMBL9765262 | 0.82 | ALDH1A1 (0.53) | KCNA5ALDH1A1ATML3MBTL1MMP2 | |
| SCHEMBL9765292 | 0.82 | CYP1A2 (0.49) | KCNA5ALDH1A1CNR1ATML3MBTL1 | |
| SCHEMBL1287475 | 0.82 | MAPT (0.58) | KCNA5ALDH1A1ATML3MBTL1MMP2 | |
| SCHEMBL15388015 | 0.82 | MAPT (0.58) | KCNA5ALDH1A1ATML3MBTL1MMP2 | |
| SCHEMBL29183283 | 0.81 | ALDH1A1 (0.55) | KCNA5ALDH1A1POLBCNR1ATM | |
| SCHEMBL9765324 | 0.80 | ALDH1A1 (0.48) | ALDH1A1POLBL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL11103819 | 0.80 | L3MBTL1 (0.53) | KCNA5ALDH1A1ATML3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |