Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073758 | 0.86 | LMNA (0.55) | CTSSCTSKHTT | |
| SCHEMBL13073762 | 0.86 | LMNA (0.55) | CTSSCTSKHTT | |
| SCHEMBL9765305 | 0.85 | LMNA (0.51) | CTSSCTSKHTT | |
| SCHEMBL6185436 | 0.83 | LMNA (0.49) | ALDH1A1CTSSCTSKHTT | |
| SCHEMBL6557654 | 0.83 | CYP3A4 (0.49) | ALDH1A1TSHRMAPTCTSSCTSK | |
| SCHEMBL5328614 | 0.82 | PPARG (0.50) | MAPTL3MBTL1CA1CA2ACHE | |
| SCHEMBL8079357 | 0.81 | CYP3A4 (0.47) | ALDH1A1TSHRMAPTCA1CA2 | |
| SCHEMBL5988161 | 0.80 | PLAU (0.50) | ALDH1A1TSHRMAPTL3MBTL1BCHE | |
| SCHEMBL9765333 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHRMAPT | |
| SCHEMBL22593378 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |