Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510767 | 0.84 | ALDH1A1 (0.54) | TSHRALDH1A1CYP2C9CYP2C19GAA | |
| SCHEMBL7924121 | 0.77 | GRIN1 (0.46) | TSHRALDH1A1ARHTTTDP1 | |
| SCHEMBL10705664 | 0.77 | TDP1 (0.55) | TSHRHTTTDP1PTGDR2GAA | |
| SCHEMBL9765272 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1ADRB3MCL1MAPK1 | |
| SCHEMBL10701921 | 0.76 | ALDH1A1 (0.56) | TSHRALDH1A1POLBMAPTKMT2A | |
| SCHEMBL9512047 | 0.75 | IDO1 (0.60) | TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9765316 | 0.75 | ALDH1A1 (0.54) | TSHRALDH1A1 | |
| SCHEMBL16832167 | 0.74 | RAB9A (0.67) | RAB9ATSHRALDH1A1HTTTDP1 | |
| SCHEMBL16832165 | 0.74 | RAB9A (0.67) | RAB9ATSHRALDH1A1HTTTDP1 | |
| SCHEMBL8789596 | 0.74 | MAPK1 (0.55) | RAB9ATSHRALDH1A1MCL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |