Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701921 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBTP53L3MBTL1 | |
| SCHEMBL9512047 | 0.78 | IDO1 (0.60) | ALDH1A1TSHRSMN1; SMN2TBXA2RTBXAS1 | |
| SCHEMBL9510767 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRGAALMNAMAPT | |
| SCHEMBL9765316 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNASMN1; SMN2TBXA2R | |
| SCHEMBL7920711 | 0.77 | FABP4 (0.50) | ALDH1A1TSHRPOLBGAAFABP4 | |
| SCHEMBL9765328 | 0.76 | RAB9A (0.51) | ALDH1A1TSHRPOLBGAAADRB3 | |
| SCHEMBL10703755 | 0.75 | CA1 (0.55) | ALDH1A1TSHRSMN1; SMN2MAPTTBXA2R | |
| SCHEMBL9765333 | 0.73 | ALDH1A1 (0.66) | ALDH1A1TSHRSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL17296536 | 0.72 | FABP4 (0.65) | ALDH1A1TSHRPOLBGAAFABP4 | |
| SCHEMBL9765332 | 0.71 | SMN1; SMN2 (0.58) | ALDH1A1TSHRPOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |