Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | MPC2 | O95563 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458654 | 0.80 | FFAR1 (0.55) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL9765576 | 0.79 | HPGD (0.57) | KDM4E | |
| SCHEMBL9223431 | 0.78 | KDM4E (0.50) | FFAR1PPARAPPARGKDM4ENPC1 | |
| SCHEMBL9832866 | 0.77 | FFAR1 (0.57) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL8316232 | 0.75 | FFAR1 (0.84) | FFAR1PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL6954017 | 0.75 | PPARA (0.47) | FFAR1PPARAPPARG | |
| SCHEMBL9558560 | 0.75 | PPARG (0.49) | FFAR1PPARGKDM4ENPC1MAPT | |
| SCHEMBL290976 | 0.74 | UTRN (0.48) | FFAR1PPARGKDM4ENPC1TP53 | |
| SCHEMBL29702319 | 0.74 | UTRN (0.48) | FFAR1PPARGKDM4ENPC1TP53 | |
| SCHEMBL8312136 | 0.74 | FFAR1 (0.87) | FFAR1PPARAPPARGMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019704-A2 | OXA- AND THIAZOLIDINEDIONE HYPOGLYCEMIC AND HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5037842-A | Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents | PFIZER INC. (US) | 1991-08-06 | — | — | US | disclosed |