Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL3816274 | 0.94 | DPP4 (0.32) | CYP2C19STSBACE1LMNADPP4 | |
| SCHEMBL3817812 | 0.91 | ALDH1A1 (0.37) | ALDH1A1STSBACE1DPP4CTDSP1 | |
| SCHEMBL28679791 | 0.80 | ALDH1A1 (0.34) | ALDH1A1BACE1USP2LMNACYP1A2 | |
| SCHEMBL26939293 | 0.80 | MEN1 (0.32) | CYP2C19 | |
| SCHEMBL26939298 | 0.79 | CYP2C19 (0.32) | ALDH1A1CYP2C19USP2LMNACYP1A2 | |
| SCHEMBL9843658 | 0.77 | ALDH1A1 (0.38) | ALDH1A1BACE1LMNADPP4 | |
| SCHEMBL26939295 | 0.77 | — | — | |
| SCHEMBL10927098 | 0.73 | ALDH1A1 (0.38) | ALDH1A1BACE1 | |
| SCHEMBL10929994 | 0.73 | ALDH1A1 (0.38) | ALDH1A1BACE1 | |
| SCHEMBL2861221 | 0.73 | ALDH1A1 (0.38) | ALDH1A1BACE1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358092-B1 | 2-AZA-4-(ALKOXYCARBONYL)SPIRO-(4,5)DECAN-3-ONE | LONZA A.G. (CH) | 1991-12-11 | — | — | EP | claimed |
| US-5068413-A | Process for the preparation of cyclic amino acids and intermediates useful in the process | GODECKE AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |