Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410772 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAJAK2S1PR4MAPT | |
| Butane SCHEMBL3816274 | 0.82 | DPP4 (0.32) | LMNABACE1DPP4 | |
| SCHEMBL3817812 | 0.82 | ALDH1A1 (0.37) | ALDH1A1BACE1DPP4 | |
| SCHEMBL28679791 | 0.79 | ALDH1A1 (0.34) | ALDH1A1LMNABACE1 | |
| SCHEMBL9765605 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNABACE1DPP4 | |
| SCHEMBL5932191 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL11406576 | 0.76 | NAAA (0.41) | ALDH1A1HTTDPP4 | |
| SCHEMBL7276909 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPTBACE1DPP4 | |
| SCHEMBL17294422 | 0.76 | OPRM1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL2861221 | 0.76 | ALDH1A1 (0.38) | ALDH1A1RAB9ABACE1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013190357-A1 | A PROCESS FOR THE PREPARATION OF GABAPENTIN | HIKAL LIMITED (IN) | 2013-12-27 | — | — | WO | disclosed |
| EP-0414262-A2 | Process for the preparation of cyclic amino anticonvulsant compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |