Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 12/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976564 | 1.00 | ALOX5AP (0.41) | ALOX5APJAK3BRD4CREBBPADORA2B | |
| SCHEMBL976688 | 0.91 | ALOX5AP (0.40) | ALOX5AP | |
| SCHEMBL976687 | 0.91 | ALOX5AP (0.40) | ALOX5AP | |
| SCHEMBL977307 | 0.86 | BRD4 (0.47) | ALOX5APJAK3BRD4CREBBP | |
| SCHEMBL977306 | 0.86 | BRD4 (0.47) | ALOX5APJAK3BRD4CREBBP | |
| SCHEMBL977715 | 0.85 | ALOX5AP (0.54) | ALOX5AP | |
| SCHEMBL977714 | 0.85 | ALOX5AP (0.54) | ALOX5AP | |
| SCHEMBL3656371 | 0.78 | ALOX5AP (0.43) | ALOX5APBRD4 | |
| SCHEMBL976521 | 0.78 | ALOX5AP (0.43) | ALOX5APBRD4 | |
| SCHEMBL974874 | 0.77 | ALOX5AP (0.44) | ALOX5APBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | ALOX5AP 47/4885JAK3 4279/4885BRD4 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.