Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934335 | 0.89 | NCF1 (0.33) | NCF1RARARARBRARG | |
| SCHEMBL6271267 | 0.87 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRALOX15CA12 | |
| SCHEMBL11136043 | 0.87 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRALOX15CA12 | |
| SCHEMBL11138006 | 0.84 | ALDH1A1 (0.47) | KDM4ENFKB1ALDH1A1TSHRALOX15 | |
| SCHEMBL1370622 | 0.80 | ALDH1A1 (0.38) | KDM4ENFKB1ALDH1A1TSHRALOX15 | |
| SCHEMBL14566120 | 0.80 | KMT2A (0.44) | ALDH1A1L3MBTL1LMNARARB | |
| SCHEMBL29106745 | 0.78 | ALDH1A1 (0.42) | NCF1KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL18470127 | 0.78 | MEN1 (0.44) | ALDH1A1TSHRALOX15L3MBTL1LMNA | |
| SCHEMBL17997013 | 0.78 | — | — | |
| SCHEMBL17564558 | 0.78 | MEN1 (0.44) | ALDH1A1TSHRALOX15L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012716-B1 | MONOCHLOROTRIAZINE DYESTUFFS OF THE PYRAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR DYEING AND PRINTING TEXTILE MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-15 | — | — | EP | claimed |
| US-5047514-A | Bireactive primary disazo dyes containing 1-amino-8-hydroxynaphthalene-3,6 Disulfonic acid as coupling component | CIBA-GEIGY CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-4939243-A | Water-soluble copper complex disazo compounds containg a chloro triazinylamino group and a group of the vinylsulfone series as fiber-reactive groups and their dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| US-4713082-A | Process for dyeing or printing textile fibre materials with reactive dye containing vinyl sulfonyl-type group and chloro-triazinyl amino group | CIBA-GEIGY CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
| US-4348318-A | DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4330469-A | Reactive dyes, processes for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| US-4270918-A | METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE | CIBA-GEIGY CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |
| US-4204056-A | Process and intermediates for preparing fiber-reactive phthalocyanine dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-05-20 | — | — | US | disclosed |
| US-4191686-A | FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |