Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358215 | 0.89 | MAPT (0.42) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9765689 | 0.87 | MAPT (0.44) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL4732623 | 0.84 | MAPT (0.62) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9391303 | 0.84 | KMT2A (0.62) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL10482906 | 0.79 | ALDH1A1 (0.55) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9393651 | 0.78 | MAPT (0.67) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL7122665 | 0.77 | MEN1 (0.54) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL7170509 | 0.76 | L3MBTL1 (0.70) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8855198 | 0.76 | MEN1 (0.56) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL11316550 | 0.75 | MAPT (0.62) | MAPTALDH1A1L3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992569-A | Reacting substituted aminoanthraquinone with malodinitrile in inert solvent in presence of titanium tetrachloride and a tert iary-amine; textile dye | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |