Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765744 | 0.87 | MAPT (0.58) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL10482980 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9358215 | 0.76 | MAPT (0.42) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL4732623 | 0.72 | MAPT (0.62) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9391303 | 0.72 | KMT2A (0.62) | MAPTALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL10782025 | 0.72 | MAOA (0.63) | MAPTALDH1A1TDP1MAPK1LMNA | |
| SCHEMBL6906411 | 0.72 | S100A4 (0.61) | MAPTALDH1A1MAPK1NSD2S100A4 | |
| SCHEMBL6899117 | 0.72 | S100A4 (0.61) | MAPTALDH1A1MAPK1NSD2S100A4 | |
| SCHEMBL31375388 | 0.72 | S100A4 (0.61) | MAPTALDH1A1MAPK1NSD2S100A4 | |
| SCHEMBL29339249 | 0.72 | EGFR (0.55) | MAPTALDH1A1TDP1EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992569-A | Reacting substituted aminoanthraquinone with malodinitrile in inert solvent in presence of titanium tetrachloride and a tert iary-amine; textile dye | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |