Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9789740 | 0.98 | TDP1 (0.47) | TDP1TP53ALDH1A1LMNAPTGS2 | |
| SCHEMBL9609000 | 0.78 | ALDH1A1 (0.48) | TDP1ALDH1A1LMNAPTGS2CYP1A2 | |
| SCHEMBL7048754 | 0.78 | TP53 (0.54) | TDP1TP53ALDH1A1PTGS2TSHR | |
| SCHEMBL219895 | 0.75 | TDP1 (0.61) | TDP1ALDH1A1LMNAPTGS2CYP1A2 | |
| SCHEMBL21881 | 0.75 | TDP1 (0.67) | TDP1TP53ALDH1A1PTGS2TSHR | |
| SCHEMBL250060 | 0.75 | — | — | |
| SCHEMBL29419578 | 0.75 | — | — | |
| SCHEMBL6653366 | 0.74 | TDP1 (0.48) | TDP1TP53ALDH1A1LMNAPTGS2 | |
| SCHEMBL7024378 | 0.74 | TP53 (0.48) | TDP1TP53ALDH1A1LMNAPTGS2 | |
| SCHEMBL29927193 | 0.74 | TP53 (0.44) | TDP1TP53ALDH1A1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61050962-A | — | — | None | — | — | JP | disclosed |
| US-5037925-A | Polymers containing aromatic-azo-aliphatic moieties capable of generating photoinitiated free radicals | THE DOW CHEMICAL COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-5006567-A | Polycarbonates with high impact strength | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| US-4929721-A | Polymerizable aromatic-azo-aliphatic compounds capable of generating photoinitiated free radicals | THE DOW CHEMICAL COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| JP-S6150962-A | POLYMERIZABLE DITHIZONE COMPOUND | TOKUYAMA SODA CO LTD | 1986-03-13 | — | — | JP | disclosed |