Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butanal SCHEMBL264581 | 0.96 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| Butanal SCHEMBL11750341 | 0.96 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| Glutaral SCHEMBL6229345 | 0.87 | LMNA (0.52) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| Glutaral SCHEMBL7886922 | 0.87 | LMNA (0.52) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| SCHEMBL11485155 | 0.86 | LMNA (0.63) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| Butanal SCHEMBL23907966 | 0.86 | LMNA (0.46) | LMNAALDH1A1TSHR | |
| Decanal SCHEMBL5144514 | 0.84 | TSHR (0.59) | LMNAALDH1A1TSHRFAAHTRPV1 | |
| Ethylene SCHEMBL11409706 | 0.83 | LMNA (0.48) | LMNAALDH1A1TSHR | |
| Ethylene SCHEMBL11209176 | 0.83 | LMNA (0.48) | LMNAALDH1A1TSHR | |
| Glycerin SCHEMBL18789079 | 0.83 | LMNA (0.43) | LMNAALDH1A1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994460-A | Treatment or prevention of disorders resulting from central nervous system anoxia | BRISTOL-MYERS SQUIBB CO. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0400661-A1 | Agents for treatment of brain ischemia | Bristol-Myers Squibb Company (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0048136-B1 | PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-06-11 | — | — | EP | disclosed |