Ethylene

Ethylene

SCHEMBL11209176

C=C.CCOC(C)OCC.O=CCCBr

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7344731 0.96 LMNA (0.52) LMNAALDH1A1TSHR
Butane SCHEMBL8184201 0.92 LMNA (0.48) LMNAALDH1A1TSHR
Ethylene SCHEMBL5155337 0.85 LMNA (0.55) LMNA
Glutaral SCHEMBL6229345 0.83 LMNA (0.52) LMNAALDH1A1TSHR
Glutaral SCHEMBL7886922 0.83 LMNA (0.52) LMNAALDH1A1TSHR
Butanal SCHEMBL9765982 0.83 LMNA (0.52) LMNAALDH1A1TSHR
SCHEMBL11485155 0.83 LMNA (0.63) LMNAALDH1A1TSHR
SCHEMBL9657661 0.82 LMNA (0.46) LMNAALDH1A1TSHR
SCHEMBL188914 0.81 LMNA (0.60) LMNAALDH1A1
Ethylene SCHEMBL11409706 0.80 LMNA (0.48) LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190336610-A1 GLUCOSE-SENSITIVE PEPTIDE HORMONES GUBRA APS (DK) 2019-11-07 US disclosed
EP-3558383-A1 GLUCOSE-SENSITIVE PEPTIDE HORMONES Gubra ApS (DK) 2019-10-30 EP disclosed
WO-2018115462-A1 GLUCOSE-SENSITIVE PEPTIDE HORMONES GUBRA APS (DK) 2018-06-28 WO disclosed
EP-0001668-B1 CYCLISATION PROCESS FOR PREPARING 11 BETA-AXIALLY-SUBSTITUTED STEROIDS AKZO N.V. (NL) 1983-05-25 EP disclosed
US-4329473-A HYPOTENSIVE AGENTS SRI INTERNATIONAL 1982-05-11 US disclosed
US-4222940-A Cyclization substrates, cyclization process and related 11β-axially-substituted steroids AKZONA INCORPORATED (US) 1980-09-16 US disclosed
EP-0001668-A2 Cyclisation process for preparing 11 beta-axially-substituted steroids AKZO N.V. (NL) 1979-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190336610-A1 GLUCOSE-SENSITIVE PEPTIDE HORMONES IAPP, GCG, VIP LMNA 456/4885ALDH1A1 3127/4885TSHR 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.