Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31379038 | 0.85 | LMNA (0.60) | ALDH1A1EGFRLMNACREBBPHSD17B10 | |
| SCHEMBL5025547 | 0.85 | ALDH1A1 (0.50) | ALDH1A1EGFRLMNAHSD17B10GLA | |
| SCHEMBL29062859 | 0.85 | LMNA (0.60) | ALDH1A1EGFRLMNACREBBPHSD17B10 | |
| SCHEMBL28558501 | 0.81 | LMNA (0.54) | ALDH1A1EGFRLMNACREBBPBRD4 | |
| SCHEMBL29894565 | 0.81 | LMNA (0.54) | ALDH1A1EGFRLMNACREBBPBRD4 | |
| SCHEMBL17969124 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LMNACREBBPHSD17B10BRD4 | |
| SCHEMBL9153385 | 0.79 | LMNA (0.54) | ALDH1A1EGFRLMNACREBBPHSD17B10 | |
| SCHEMBL29960617 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNACREBBPHSD17B10BRD4 | |
| SCHEMBL25789187 | 0.79 | BRD4 (0.57) | ALDH1A1LMNACREBBPHSD17B10BRD4 | |
| SCHEMBL23824580 | 0.79 | IDO1 (0.61) | ALDH1A1LMNACREBBPBRD4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |