Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766028 | 0.85 | ALDH1A1 (0.60) | ALDH1A1EGFRTP53L3MBTL1GLA | |
| SCHEMBL5025468 | 0.81 | CRBN (0.45) | CRBNDDB1FFAR1PPARDTP53 | |
| SCHEMBL6443098 | 0.80 | CRBN (0.44) | ALDH1A1EGFRCRBNDDB1LMNA | |
| SCHEMBL6441308 | 0.80 | CRBN (0.44) | ALDH1A1EGFRCRBNDDB1LMNA | |
| SCHEMBL8524142 | 0.80 | CRBN (0.46) | ALDH1A1CRBNDDB1NPC1MAPK13 | |
| SCHEMBL29960387 | 0.80 | CRBN (0.47) | ALDH1A1CRBNDDB1NPC1MAPK13 | |
| Hydrochloric Acid SCHEMBL29960573 | 0.79 | CRBN (0.46) | ALDH1A1CRBNDDB1NPC1MAPK13 | |
| SCHEMBL28979267 | 0.78 | AOC3 (0.43) | ALDH1A1EGFRCRBNDDB1LMNA | |
| SCHEMBL8367985 | 0.77 | EGFR (0.45) | ALDH1A1EGFRFFAR1PPARDTP53 | |
| SCHEMBL13652133 | 0.77 | ALDH1A1 (0.71) | ALDH1A1CRBNDDB1NPC1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | ALDH1A1 2222/4885EGFR 356/4885CRBN 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.