SCHEMBL9766039

SCHEMBL9766039

COc1c(F)c(C)c(F)c(OC)c1CO

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
IMPDH2 P12268 4/20 0.35
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9766119 0.91 CA2 (0.41) CA2CA4IMPDH2
SCHEMBL9766027 0.86 CA2 (0.46) CA2CA4IMPDH2
SCHEMBL28274628 0.83 CA2 (0.41) CA2CA4IMPDH2
SCHEMBL21230374 0.82 CA2 (0.37) CA2CA4IMPDH2
SCHEMBL9766111 0.77 CA2 (0.43) CA2CA4IMPDH2
SCHEMBL357480 0.76 CA2 (0.46) CA2CA4IMPDH2
SCHEMBL9108639 0.75 CA2 (0.54) CA2CA4AKR1B1
SCHEMBL16071629 0.75 HSD17B10 (0.32) IMPDH2
SCHEMBL9785635 0.72 CA2 (0.39) CA2CA4
SCHEMBL9766074 0.72 CA2 (0.39) CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266947-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-04 EP disclosed
US-4853414-A 1-/2-ALKOXY-3,5-DIFLUOROBENZYL ESTERS OF 2,2-DIMETHYL-3-ALKYLCYCLOPROPIONIC ACID; INSECTICIDES; PESTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-01 US disclosed
EP-0266947-A2 Halogenated esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed