Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 4/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | PDE5A | O76074 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971157 | 0.84 | CA2 (0.46) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL9766027 | 0.78 | CA2 (0.46) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL10130850 | 0.77 | CA2 (0.50) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL9766039 | 0.75 | CA2 (0.43) | CA2CA4AKR1B1 | |
| SCHEMBL5533935 | 0.73 | CA2 (0.69) | CA2CA4CA1CA6PDE1A | |
| SCHEMBL9962327 | 0.73 | CA2 (0.46) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL357480 | 0.73 | CA2 (0.46) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL9549629 | 0.73 | CA2 (0.46) | CA2CA4MAPTAKR1B1 | |
| SCHEMBL6439100 | 0.73 | CA2 (0.46) | CA2CA4MAPTCA1CA6 | |
| SCHEMBL26566932 | 0.73 | CA2 (0.46) | CA2CA4MAPTCA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529089-B1 | THICK RADIATION SENSITIVE DEVICES | JP LAB INC (US) | 2012-06-06 | — | — | EP | claimed |