Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785635 | 0.92 | CA2 (0.39) | CA2CA4GCGR | |
| SCHEMBL359266 | 0.85 | GCGR (0.39) | CA2CA4GCGRIGF1RSRC | |
| SCHEMBL9785382 | 0.83 | CA2 (0.36) | CA2CA4 | |
| SCHEMBL9766196 | 0.83 | GCGR (0.33) | GCGR | |
| SCHEMBL9785640 | 0.82 | CA2 (0.35) | CA2CA4 | |
| SCHEMBL9766111 | 0.81 | CA2 (0.43) | CA2CA4 | |
| SCHEMBL27833797 | 0.81 | HSD17B10 (0.32) | CA2CA4 | |
| SCHEMBL19688655 | 0.78 | GCGR (0.36) | GCGRIGF1RSRCAXLPTK2 | |
| SCHEMBL9766119 | 0.78 | CA2 (0.41) | CA2CA4 | |
| SCHEMBL7107814 | 0.78 | IGF1R (0.31) | GCGRIGF1RSRCAXLPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266947-B1 | HALOGENATED ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4853414-A | 1-/2-ALKOXY-3,5-DIFLUOROBENZYL ESTERS OF 2,2-DIMETHYL-3-ALKYLCYCLOPROPIONIC ACID; INSECTICIDES; PESTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4762835-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-09 | — | — | US | disclosed |
| EP-0266947-A2 | Halogenated esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-11 | — | — | EP | disclosed |
| EP-0227415-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |