Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MPL | P40238 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156787 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8210777 | 0.83 | KMT2A (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8366255 | 0.81 | KDM4E (0.67) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9152213 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31376496 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8366302 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23118890 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4112149 | 0.80 | KDM4E (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6116786 | 0.78 | TSHR (0.69) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9766056 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |