SCHEMBL359266

SCHEMBL359266

COCc1c(F)c(F)c(CO)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.39
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
IGF1R P08069 1/20 0.31
SRC P12931 1/20 0.31
AXL P30530 1/20 0.31
PTK2 Q05397 1/20 0.31
AURKB Q96GD4 1/20 0.31
ALK Q9UM73 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL22129233 0.89 PRKCE (0.36) GCGRIGF1RSRCAXLPTK2
SCHEMBL19688655 0.87 GCGR (0.36) GCGRIGF1RSRCAXLPTK2
SCHEMBL29843338 0.87 GCGR (0.36) GCGRIGF1RSRCAXLPTK2
SCHEMBL7107814 0.87 IGF1R (0.31) GCGRIGF1RSRCAXLPTK2
Propionic Acid SCHEMBL22160486 0.86 FFAR3 (0.37) GCGR
SCHEMBL19478317 0.85 CA2 (0.39) GCGRCA2CA4
SCHEMBL9785635 0.85 CA2 (0.39) GCGRCA2CA4
SCHEMBL9766074 0.85 CA2 (0.39) GCGRCA2CA4IGF1RSRC
SCHEMBL19478240 0.85 GCGR (0.35) GCGR
SCHEMBL19688660 0.84 GCGR (0.36) GCGRIGF1RSRCAXLPTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113348161-B Method for producing ester compound 住友化学株式会社 2023-11-28 CN claimed
CN-114106304-A Low-temperature curing weather-resistant polyester resin, low-temperature curing weather-resistant powder coating and preparation method 安徽神剑新材料股份有限公司 2022-03-01 CN claimed
CN-113348161-A Method for producing ester compound 住友化学株式会社 2021-09-03 CN claimed
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-08-18 US claimed
WO-2020158047-A1 METHOD FOR PRODUCING ESTER COMPOUND 住友化学株式会社 2020-08-06 WO claimed
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-07-02 US claimed
WO-2020124727-A1 SYNTHESIS METHOD FOR 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL 浙江中欣氟材股份有限公司 2020-06-25 WO claimed
CN-109438234-B Synthetic method of 2,3,5, 6-tetrafluoro-4-methoxymethyl benzyl alcohol 浙江中欣氟材股份有限公司 2020-04-21 CN claimed
CN-104628570-A Clean production method of meperfluthrin JIANGSU YANGNONG CHEMICAL CO 2015-05-20 CN claimed
CN-104628571-A Meperfluthrin production method with clean synthetic process JIANGSU YANGNONG CHEMICAL CO 2015-05-20 CN claimed
CN-102731269-B Synthesis method of 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-04-02 CN claimed
US-8629296-B2 Pyrethroid compound, preparation process and use thereof JIANGSU YANGNONG CHEMICAL CO., LTD. (CN) 2014-01-14 US claimed
CN-102153474-B Ester compound for preventing and controlling animal parasites, and preparation method and application thereof JIANGSU YANGNONG CHEMICAL CO 2013-11-13 CN claimed
US-20120076846-A1 Pyrethroid Compound, Preparation Process and Use Thereof JIANGSU YANGNONG CHEMICAL CO. LTD. (CN) 2012-03-29 US claimed
EP-1110938-B1 Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL CO (JP) 2003-11-05 EP claimed
US-6339176-B2 BY REACTING 2,3,5,6-TETRAFLUORO-1,4-BENZENEDIMETHANOL WITH AN INORGANIC BASE IN WATER, ADDING DIMETHYL SULFATE AND A WATER IMMISCIBLE ORGANIC SOLVENT OF EITHER HYDROCARBONS OR ETHERS TO THE REACTION MIXTURE; INSECTICIDES; MONOMETHYLATION SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2002-01-15 US claimed
EP-1110938-A1 Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-27 EP claimed
US-20010003138-A1 Method for producing 4-methoxymethy1-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-07 US claimed
US-4661488-A Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-28 US claimed
EP-0162538-A2 Cyclopropane derivates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010003138-A1 Method for producing 4-methoxymethy1-2,3,5,6-tetrafluorobenzenemethanol MSMO1, TDO2, PMM2 GCGR 4737/4885CA2 1065/4885CA4 456/4885
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol TET2, TH, ALKBH2 GCGR 4661/4885CA2 1199/4885CA4 683/4885
US-20120076846-A1 Pyrethroid Compound, Preparation Process and Use Thereof DDT, PTMA, CYP51A1 GCGR 3662/4885CA2 870/4885CA4 1483/4885
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL TH, ALKBH2, ALKBH3 GCGR 4714/4885CA2 1650/4885CA4 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.