SCHEMBL19688655

SCHEMBL19688655

COCc1c(F)c(C)c(CO)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.36
IGF1R P08069 1/20 0.34
SRC P12931 1/20 0.34
AXL P30530 1/20 0.34
PTK2 Q05397 1/20 0.34
AURKB Q96GD4 1/20 0.34
ALK Q9UM73 1/20 0.34
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19688660 0.94 GCGR (0.36) GCGRIGF1RSRCAXLPTK2
SCHEMBL359266 0.87 GCGR (0.39) GCGRIGF1RSRCAXLPTK2
SCHEMBL457595 0.80 IGF1R (0.35) IGF1RSRCAXLPTK2AURKB
SCHEMBL7107814 0.79 IGF1R (0.31) GCGRIGF1RSRCAXLPTK2
SCHEMBL19478240 0.78 GCGR (0.35) GCGR
Acetic Acid SCHEMBL22129233 0.78 PRKCE (0.36) GCGRIGF1RSRCAXLPTK2
SCHEMBL19478317 0.78 CA2 (0.39) GCGR
SCHEMBL9766074 0.78 CA2 (0.39) GCGRIGF1RSRCAXLPTK2
SCHEMBL359564 0.77 GCGR (0.30) GCGR
SCHEMBL14708745 0.77 CA12 (0.32) IGF1RSRCAXLPTK2AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195944-B Ester compound and use thereof 大日本除虫菊株式会社 2022-06-14 CN disclosed
WO-2017208632-A1 ESTER COMPOUND AND USE THEREOF 大日本除蟲菊株式会社 2017-12-07 WO disclosed