SCHEMBL9766213

Nc1nc2c(sc(=S)n2[C@@H]2O[C@H](C(O)C(=O)c3ccccc3)[C@](O)(C(=O)c3ccccc3)[C@]2(O)C(=O)c2ccccc2)c(=O)[nH]1

nearest known ligand 0.43

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TLR7	Q9NYK1	20/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10581458	0.93	TLR7 (0.48)	TLR7
SCHEMBL10576885	0.88	TLR7 (0.40)	TLR7
SCHEMBL10579570	0.80	ALDH1A1 (0.35)	TLR7
SCHEMBL10576397	0.79	TLR7 (0.34)	TLR7
Hydrochloric Acid SCHEMBL11628085	0.72	PDE3A (0.40)	—
SCHEMBL4890432	0.71	ALDH1A1 (0.32)	—
SCHEMBL794862	0.71	P2RY2 (0.31)	—
SCHEMBL9221120	0.69	NT5E (0.36)	—
SCHEMBL6256517	0.69	NT5E (0.36)	—
SCHEMBL6905328	0.69	TLR7 (0.47)	TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0348446-A4	ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES	—	1991-09-25	—	—	EP	disclosed
EP-0348446-A1	ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES.	UNIV BRIGHAM YOUNG (US)	1990-01-03	—	—	EP	disclosed
US-4880784-A	ANTITUMOR AGENTS	BRIGHAM YOUNG UNIVERSITY (US)	1989-11-14	—	—	US	disclosed
WO-1989005649-A1	ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES	BRIGHAM YOUNG UNIVERSITY (US)	1989-06-29	—	—	WO	disclosed