Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794862 | 0.78 | P2RY2 (0.31) | ALDH1A1POLBMAPT | |
| SCHEMBL9221120 | 0.74 | NT5E (0.36) | POLB | |
| SCHEMBL6256517 | 0.74 | NT5E (0.36) | POLB | |
| SCHEMBL10576885 | 0.73 | TLR7 (0.40) | — | |
| SCHEMBL9223581 | 0.72 | RNASE1 (0.44) | ALDH1A1POLB | |
| SCHEMBL5080723 | 0.72 | LMNA (0.36) | MAPT | |
| SCHEMBL9766213 | 0.71 | TLR7 (0.43) | — | |
| SCHEMBL11390388 | 0.71 | CDA (0.38) | — | |
| SCHEMBL5610629 | 0.70 | RNASE1 (0.32) | — | |
| SCHEMBL10579570 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008522968-A | — | — | 2008-07-03 | — | — | JP | claimed |
| EP-1824855-A1 | NOVEL PYRROLO [3, 2-D]PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THERAPY | AstraZeneca AB (SE) | 2007-08-29 | — | — | EP | claimed |
| WO-2006062465-A1 | NOVEL PYRROLO [3, 2-D] PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-06-15 | — | — | WO | claimed |