Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221120 | 0.90 | NT5E (0.36) | P2RY2P2RY4P2RY6POLB | |
| SCHEMBL6256517 | 0.90 | NT5E (0.36) | P2RY2P2RY4P2RY6POLB | |
| SCHEMBL9223581 | 0.81 | RNASE1 (0.44) | ALDH1A1POLB | |
| SCHEMBL5080723 | 0.81 | LMNA (0.36) | P2RY6MAPT | |
| SCHEMBL2014365 | 0.80 | CYP3A4 (0.38) | P2RY2P2RY4POLB | |
| SCHEMBL20822313 | 0.80 | CYP3A4 (0.38) | P2RY2P2RY4POLB | |
| SCHEMBL5610629 | 0.80 | RNASE1 (0.32) | P2RY2 | |
| SCHEMBL8367093 | 0.79 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL4890432 | 0.78 | ALDH1A1 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL9237423 | 0.78 | ABL1 (0.31) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2787999-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL DISEASES | The Board of Trustees of The Leland Stanford Junior University (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013086133-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL DISEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-06-13 | — | — | WO | disclosed |
| EP-2491033-A2 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | Eiger Biopharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2012037485-A2 | METHODS OF INHIBITING ALPHAVIRUS REPLICATION AND TREATING ALPHAVIRUS INFECTION | 1THE JOHNS HOPKINS UNIVERSITY (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011049987-A2 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | EIGER BIOPHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011049988-A2 | INDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | EIGER BIOPHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | WO | disclosed |