⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926219 | 0.97 | — | — | |
| Potassium Ion SCHEMBL3897706 | 0.95 | — | — | |
| SCHEMBL937334 | 0.95 | — | — | |
| Potassium Ion SCHEMBL3131828 | 0.92 | — | — | |
| Potassium Ion SCHEMBL5803916 | 0.82 | SLC34A1 (0.32) | — | |
| SCHEMBL9098975 | 0.78 | — | — | |
| Tetrabuthylammonium SCHEMBL2824667 | 0.75 | SLC22A1 (0.41) | — | |
| Potassium Ion SCHEMBL5689772 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL4523855 | 0.72 | TPI1 (0.34) | — | |
| Ammonia Solution, Strong SCHEMBL10847788 | 0.72 | TPI1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185138-B1 | SOLID PREPARATION COMPRISING ALOGLIPTIN AND METFORMIN HYDROCHLORIDE | TAKEDA PHARMACEUTICAL (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-20110014299-A2 | SOLID PREPARATION COMPRISING ALOGLIPTIN AND METFORMIN HYDROCHLORIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
| EP-2185138-A1 | SOLID PREPARATION COMPRISING ALOGLIPTIN AND METFORMIN HYDROCHLORIDE | Takeda Pharmaceutical Company Limited (JP) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009011451-A1 | SOLID PREPARATION COMPRISING ALOGLIPTIN AND METFORMIN HYDROCHLORIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-22 | — | — | WO | disclosed |