Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3897706 | 0.97 | — | — | |
| SCHEMBL937334 | 0.97 | — | — | |
| SCHEMBL926219 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL976623 | 0.92 | — | — | |
| Potassium Ion SCHEMBL5803916 | 0.89 | SLC34A1 (0.32) | — | |
| SCHEMBL9098975 | 0.80 | — | — | |
| Potassium Ion SCHEMBL5689772 | 0.80 | — | — | |
| Tetrabuthylammonium SCHEMBL2824667 | 0.77 | SLC22A1 (0.41) | — | |
| SCHEMBL6645670 | 0.75 | TSHR (0.38) | — | |
| Potassium Ion SCHEMBL5807703 | 0.74 | TPI1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105603016-B | A method of S-Leucine is prepared using leucine dehydrogenase coupling glucose dehydrogenase | 江南大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-105603016-A | Method for preparing L-tert-leucine by coupling leucine dehydrogenase with glucose dehydrogenase | UNIV JIANGNAN | 2016-05-25 | — | — | CN | disclosed |
| WO-2010013925-A2 | PHARMACOLOGICAL COMPOSITION FOR PREVENTION AND TREATMENT OF RESPIRATORY DISEASE CONTAINING PYRAZOLOPYRIMIDINONE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | DONG-A PHARMACEUTICAL. CO., LTD. (KR) | 2010-02-04 | — | — | WO | disclosed |
| US-7378555-B2 | Method of synthesizing camptothecin-relating compounds | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20070010674-A1 | Method of synthesizing camptothecin-relating compounds | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2007-01-11 | — | — | US | disclosed |
| US-7126000-B2 | Method of synthesizing camptothecin-relating compounds | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040106830-A1 | Method of synthesizing camptothecin-relating compounds | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1378505-A1 | METHOD OF SYNTHESIZING CAMPTOTHECIN-RELATING COMPOUNDS | Kabushiki Kaisha Yakult Honsha (JP) | 2004-01-07 | — | — | EP | disclosed |
| EP-1029863-B1 | CAMPTOTHECIN DERIVATIVES | YAKULT HONSHA KK (JP) | 2003-05-14 | — | — | EP | disclosed |
| EP-1022277-B1 | NEW TAXANE DERIVATIVES | YAKULT HONSHA KK (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6310210-B1 | WATER-SOLUBLE AND EXCELLENT IN AN ANTI-TUMOR ACTIVITY | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-10-30 | — | — | US | disclosed |
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6136808-A | ANTITUMOR AGENTS FROM PLANTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1029863-A1 | NOVEL CAMPTOTHECIN DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-08-23 | — | — | EP | disclosed |
| EP-1022277-A1 | NEW TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-6025385-A | HIGH SOLUBILITY IN WATER AND ALSO HAS EXCELLENT ANTITUMOR ACTIVITIES. | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0930309-A1 | TAXANE DERIVATIVES AND DRUGS CONTAINING THE SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1999-07-21 | — | — | EP | disclosed |