Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27094502 | 0.92 | RIPK1 (0.53) | RIPK1LMNAALDH1A1DHFRKDM4E | |
| SCHEMBL1520904 | 0.92 | RIPK1 (0.53) | RIPK1LMNAALDH1A1DHFRKDM4E | |
| SCHEMBL6577441 | 0.86 | DUT (0.38) | RIPK1DUTALDH1A1KDM4E | |
| SCHEMBL6577339 | 0.84 | SMN1; SMN2 (0.40) | LMNAL3MBTL1 | |
| SCHEMBL8109598 | 0.84 | DUT (0.36) | RIPK1DUT | |
| SCHEMBL13527885 | 0.83 | SIGMAR1 (0.44) | DUT | |
| SCHEMBL1154991 | 0.82 | RIPK1 (0.47) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL14878508 | 0.82 | RIPK1 (0.47) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL5468442 | 0.82 | RIPK1 (0.49) | RIPK1LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6577204 | 0.81 | CYP2C19 (0.39) | LMNADUTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071469-A | Pre- and postemergence plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0394059-A1 | Herbicidal benzylsulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-24 | — | — | EP | disclosed |